| NewsRx.com,
February 16, 2006
Vaccination
against foot-and-mouth disease virus confers complete
clinical protection in seven days and partial
protection in four days.
According to
researchers in the United States and England,
"Recent outbreaks of foot-and-mouth disease virus
(FMDV) demonstrate that this highly contagious viral
infection of cloven hoofed animals continues to be a
significant economic problem worldwide. Debate about
the most effective way to respond to outbreaks of FMDV
in disease free countries continues to center on the
use of vaccines. In this report, we present data
showing that a commercially available, standard dose
vaccine formulation can fully protect cattle against
direct challenge with the virus in as little as seven
days with no carrier transmission to naive
animals."
"Cattle
challenged four days after vaccination have reduced
disease severity, no detectable virus in blood and
little virus shedding from nasal secretions,"
said William T. Golde at the U.S. Department of
Agriculture and collaborators in the U.S. and England.
"These significant effects at four days post
vaccination, confirmed in two separate trials, support
the value of using currently available vaccines as a
first line of defense against foot-and-mouth disease (FMD)
outbreaks."
Golde
and his coauthors published the results of their
research in Vaccine (Vaccination against
foot-and-mouth disease virus confers complete clinical
protection in seven days and partial protection in
four days: Use in emergency outbreak response.
Vaccine, 2005;23(50):5775-5782).
For
additional information, contact William T. Golde, Plum
Island Animal Disease Center, Foot-and-Mouth Disease
Unit U.S. Department of Agriculture ARS, PO Box 848,
Greenport, NY 11944, USA. E-mail: wgolde@piadc.ars.usda.gov. |
